A field experiment was conducted during 2016-17 and 2017-18 at Hill Agricultural Research and Extension Centre, Bajaura (Himachal Pradesh), India to study the response of wheat (Tritucum aestivum L.) to different herbicidal treatments. The experiment was conducted in a randomized block design with eleven treatments and in three replications. The experimental results revealed that application of pre-mix herbicide Metsulfuron + Carfentrazone + Surfactant at 32 days after sowing recorded the maximum degree of reduction in the density as well as dry matter of broad-leaved weeds at 30 DAS compared to the remaining treatments. A significantly higher yield attributes of wheat were recorded in Metsulfuron + Carfentrazone + Surfactant treatment while significantly yield attributes of wheat was recorded in weedy check treatment. Higher yield (straw and grain) and weed control efficiency of wheat was recorded in Metsulfuron + Carfentrazone + Surfactant treatment while lower grain yield, straw yield and weed control efficiency was recorded in weedy check. Hence, highest gross returns (142.6 × 103 INR ha-1), net returns (100.1 × 103 INR ha-1) and B: C ratio (2.35) were obtained from Metsulfuron + Carfentrazone + Surfactant treatment 4 + 20 g a.i. ha 1 treatment.