Salinity stress is a major abiotic factor that adversely affects soybean (Glycine max) growth and productivity. Seed priming is a cost-effective and sustainable approach to enhance crop performance under stress conditions. This study investigates the potential of three seed priming agents, namely Salicylic acid (100, 250, 500, 1000µM), Potassium chloride (50, 100, 250, 500mM) and Paclobutrazol (100, 250, 500, 1000µM), in alleviating the negative impacts of salinity stress of 6dS/m on soybean seed growth and development. The physiological parameters such as, germination, mean seedling length, seedling dry weight, Vigor index-I and II and early vigor parameters viz, mean germination time, speed of germination and coefficient of velocity of germination were compared with hydro-primed and unprimed seeds. The results of the study demonstrated that when salicylic acid primed seeds at 1000µM were exposed to 6dS/m, has significantly enhanced the seed germination (80%) and other physiological parameters such as MSL (13.22cm), vigor index- I and II (977.86 and 1036) reduced MGT (2days) in a salt susceptible variety, SL958 as compared to KCl and Paclobutrazol. However, KCl at 100mM and PBZ at 500 µM had higher germination % as compared to other doses. Salicylic acid priming enhanced the antioxidant defense system, reducing oxidative damage caused by salinity stress. Hence, current findings suggest that the use of salicylic acid as a seed priming agents can be a promising strategy for mitigating salinity stress in soybean cultivation.