The selection method against drought stress using PEG in the vegetative phase was used to simulate maize tolerance to drought stress in the vegetative phase. The main objective of this research was to determine the response of maize genotypes that were tolerant and sensitive to drought stress in the vegetative phase. The research was conducted at the Greenhouse, Agrotechnology Study Program, Trunojoyo University, Madura – Indonesia. The planting materials consisted of twenty maize genotypes, consisting of fifteen Madura-Indonesian local maize genotypes, and five national-Indonesian varieties (Srikandi Kuning, Sukmaraga, BISI-2, PIONEER 21, and Anoman). The research design used a factorial randomized complete block design. The first factor was twenty maize genotypes, while the second factor was the giving of PEG- 6000 solution with a concentration of 10% which was equivalent to -0.19 Mpa. The results of the vegetative phase selection of drought stress- tolerant maize genotypes revealed that G3, G4, G8, and G11 were tolerant genotypes, whereas G1, G2, G5, G6, G7, G9, G10, G12, G13, G14, and G15 were drought-sensitive genotypes.