In JNKVV, Jabalpur, a research was conducted to examine the effects of biodynamic preparations in the context of comparisons of conventional, organic, and biodynamic systems and varied varieties of wheat. Seven BOP (bio-organic preparations) served as the treatments of main plot for the experiment's split plot design, while four different wheat varieties served as the sub plot treatments, each of which was replicated thrice. Observations based on plant population, various crop’s growth studies were noted at the 30, 60, 90 DAS and at the harvest. However, the crop growth rate (CGR), relative growth rate (RGR) and net assimilation rate (NAR) was computed at 30-60 and 60-90 days intervals. The yield attributing characteristics viz., length of ear head, number of effective tillers per meter square, no. of grains per ear head, weight of grains per ear head, and the test weight and finally grain and straw’s yield were recorded at harvest. Finally, the economic viability of treatments were determined in the terms of gross monetary returns, cost cultivation, net monetary returns and benefit- cost BC ratio on the per hectare area basis. Data pertaining to the various parameters subjected to the statistical analysis for the interpretation of the results. The combined application of BD500+BD501+P+VC was succeeded by P+VC and BD500+BD501+VC, gave a notable increase of 22.29, 18.26, and 6.38 per cent on grain yield of wheat over the sole application of BD500, BD501, and P each with VC. Considerably higher grain (2462.18 kg per ha) and straw yields (3149.88 kg per ha), including harvest index (HI) (43.73). In terms of profitability, BD500+BD501+P+VC was superior to BD: 500+BD: 501+VC and P+VC. Aside from that, it was noted that the use of BD-500+BD-501 or P+VC in JW-3020 and HW-2004 as well as BD500+BD-01+P or P+VC in C-306 and Sujata stood more lucrative.