Liposarcoma was diagnosed cytologically in clinical samples of 81 dogs, constituting 1.44% of all tumours diagnosed during the period. The highest frequency was recorded in Labrador Retrievers, non descript and Spitz breeds, male dogs and in dogs aged 5–10 years or older in breed, sex and age wise analysis of tumour incidence. In cytological studies, round to ovoid to spindloid to polyhedral neoplastic cells containing round to spherical nuclei with central to eccentric placement, prominent nucleoli and pale or faintly basophilic cytoplasm with variable sized vacuolation were seen along with visible mitotic figures which were suggestive of liposarcoma. In histopathological examination, the tumors comprised pleomorphic round to polyhedral cells arranged in clusters or sheets, bearing hyperchromatic, vesicular nuclei located centrally or marginally, eosinophilic cytoplasm containing fine-to-large vacuoles, and mitoses which were confirmative of liposarcoma.