The potential influence of Moringa oleifera leaf meal on the performance and cost economics of layer Japanese quails was evaluated in the year 2020-21. A sufficient quantity of crude protein (30.21%) and fiber (8.12%) were found in the M. oleifera leaf meal. Statistical analysis at the end of sixteen weeks experiment revealed that growth characteristics, nutrient utilization, production, and carcass characters exhibited significantly enhanced values in M. oleifera leaf meal-incorporated diets. The liver and kidney function tests exhibited no organ toxicities in the birds following the dietary incorporation of M. oleifera leaf meal. On top of it, M. oleifera leaf meal-incorporated diets showed a reduction in feed cost per kg egg production in the range of Rs. 20.91-56.17. Of various inclusion levels used in the experiment, 2% was found best for all the parameters studied. At last, M. oleifera leaf meal can be recommended in the diet of layer Japanese quails as a safer, eco-friendly, and cost-effective technology.