Potato (Solanum tuberosum L.) is a significant cash and staple crop in Meghalaya, contributing to both local food security and agricultural economies. However, its cultivation faces persistent challenges from fungal diseases, among which early blight, caused primarily by Alternaria solani and occasionally by Alternaria alternata, stands out as a major constraint to production. This disease manifests as necrotic lesions with concentric rings on leaves, stems, and tubers, leading to premature defoliation, reduced photosynthetic capacity, and substantial yield losses. In the present study, an early blight pathogen, Alternaria solani, was isolated from infected potato plants collected from fields in the vicinity of the College of Post Graduate Studies in Agricultural Sciences (CPGS-AS), Umiam, Meghalaya. The isolation and morphological identification of this native putative pathogen were followed by in vitro screening against a range of essential oils to evaluate their antifungal efficacy. Among various essential oils evaluated via the poisoned food technique, clove oil demonstrated complete (100%) inhibition of the pathogen at all concentrations (500, 1000, and 1500 ppm), followed by ginger oil at higher concentrations. This effort aims to identify effective, eco-friendly alternatives to synthetic fungicides for the sustainable management of early blight, tailored to the specific pathogen prevalent in the local agroecological conditions of the region.