Water hyacinth (Eichornia crassipe) is a strongly invasive aquatic species that have great impacts on the economy, society, and environment. Water hyacinth treatment is an urgent and long-term issue. Organic composting from water hyacinth has been identified as one of the easiest and most eco-friendly methods for transferring nutrients to the plant’s growth cycle. Additionally, hydroponics is a method of growing plants according to new technology for high productivity and food safety. In this research, we combined the hydroponic growing method with the use of organic water hyacinth planting media for growing lettuce (Lactuca sativa), leaf mustard (Brassica intergrifolia) and tomato (Solanum lycopersicum). The results showed that water hyacinth planting media mixed with coir greatly influences on the growth and productivity of hydroponic lettuce, leaf mustard, and tomato. The mixture of water hyacinth and coir in a ratio of 50%:50% is the most suitable method for growing lettuce, and leaf mustard on a nutrient film technique system. Lettuce and leaf mustard growing on a water hyacinth planting media experienced an increase in root weight and length. The mixture of water hyacinth and coir in a ratio of 75%:25% is the most suitable for growing tomatoes (Solanum lycopersicum). Tomato growing on a water hyacinth planting media has an increased sprouting rate, a shortens flowering time, an increased flower number, and improves the rate of fruiting as well as enhances productivity. The nitrate content in all obtained samples satisfies WHO’s safety standards; furthermore, the lead, mercury, arsenic, and cadmium contents are not detected in the vegetable samples.