A field experiment was conducted during rabi, 2021-22 at Agricultural College Farm, Bapatla to assess the response of macro and micronutrients on growth and yield of groundnut in coastal sandy soil. The experiment was laid out in RBD with seven treatments replicated thrice. The treatments are T1- Control, T2- 100% RDF, T3- 125% RDF, T4- 100% RDF + Soil application of ZnSO4 @ 50 kg ha-1 and Borax @ 10 kg ha-1, T5- 125% RDF + Soil application of ZnSO4 @ 50 kg ha-1 and Borax @ 10 kg ha-1, T6- 100% RDF + Foliar application of ZnSO4 @ 2 g L-1, FeSO4 @ 5 g L-1 and Borax @ 1.5 g L-1 at 45 and 65 DAS, T7- 125% RDF + Foliar application of ZnSO4 @ 2 g L-1, FeSO4 @ 5 g L-1 and Borax @ 1.5 g L-1 at 45 and 65 DAS. The results indicated that there was a significant influence on dry matter production, number of pods per plant and yield and quality parameters such as oil yield and protein content by the application of macro and micronutrients. The maximum dry matter accumulation, number of pods per plant, haulm, pod and kernel yield were obtained by the treatment T7 which received 125% RDF + Foliar application of ZnSO4 @ 2 g L-1, FeSO4 @ 5 g L-1 and Borax @ 1.5 g L-1 at 45 and 65 DAS. However, the growth parameters such as plant height, number of primary branches, number of compound leaves and yield attributes such as shelling percentage and 100- kernel weight and oil content were not significantly influenced by the macro and micronutrients application.