Obesity is a significant global public health issue, with Saudi Arabia reporting notably high prevalence rates. This condition elevates the risk of chronic diseases, prompting the popularity of slimming pills as a perceived convenient weight management option. Despite their appeal, slimming pills are associated with adverse effects such as cardiovascular complications, liver toxicity, and gastrointestinal disturbances. Public awareness about these risks, however, remains limited. This study investigates community knowledge, perceptions, and practices related to slimming pills in Saudi Arabia. It examines the influence of demographic factors and aims to identify prevalent misconceptions to guide effective public health strategies. A cross-sectional quantitative study was conducted with 2,570 participants aged 18 years and above in Saudi Arabia. Data were gathered via an online questionnaire disseminated through social media platforms. Descriptive and inferential statistical analyses, including chi-square tests and logistic regression, were performed using SPSS version 26.0 to identify associations between demographic variables and participants' knowledge and perceptions. The sample predominantly consisted of females (72%) and individuals aged 18-24 years (36.43%). While 89.49% of participants were aware of slimming pills, only 29.18% considered them safe. Over 77% recognized potential adverse effects, and 26.08% reported personal or observed side effects. Social media (41.79%) was identified as the primary source of information, though 65.96% expressed low confidence in the reliability of this information. Logistic regression analysis revealed that awareness significantly predicted beliefs in adverse effects (β = 1.4183, p < 0.001), while higher education levels and existing health conditions correlated with reduced risk concerns. Although awareness of slimming pills is high, significant gaps in community knowledge and misconceptions about their safety persist. Reliance on unverified information sources remains a critical barrier to safe weight management practices. Public health interventions, including culturally appropriate educational campaigns and stricter regulation of online health content, are essential to address these issues and promote informed practices.