A field experiment was conducted to evaluate the effects of different plastic mulches and botanicals on the incidence of pests and diseases of okra var. Arka Anamika at Uttar Banga Krishi Viswavidyalaya, West Bengal, India, during 2021 and 2022. The experiment included two factors, viz., the first factor- mulches (four levels) and the second factor- botanicals (five levels). The experiment was performed in a factorial randomized complete block design with three replications. The results of the experiment revealed that the treatment comprising silver plastic mulch along with foliar spray of Azadirachta indica leaf extract (5%) (M2B1) was most effective at reducing the incidence of yellow vein mosaic virus (1.82%), cercospora leaf spot (11.39%), whitefly population (30.94%, 43.49% and 57.29% reduction at 30, 45 and 60 DAS), jassid population (30.20%, 41.95% and 52.67% reduction at 30, 45 and 60 DAS) and fruit borer population (2.17) compared to the other treatment combinations. Hence, treatment with M2B1 (silver plastic mulch × 5% foliar spray of Azadirachta indica leaf extract) appears to be an effective eco-friendly approach for reducing pest and disease incidence and can be recommended for the commercial cultivation of okra in terai region of West Bengal.