The present study was conducted at ICAR-Central Horticultural Experiment Station (CIAH-RS), Godhra, Gujarat during 2021-2022. The correlation coefficients among antioxidants, nutritional and physiological traits of bottle gourd varieties calculated and summarized by using the BLUPs. A strong positive correlation was found in CUPRAC with DPPH (r=1.00; P≤0.01). High mag-nitude and non significant correlation was found in TF with CUPRAC and DPPH (r = +0.96). Among 29 physiological traits in bottle gourd varieties, highly significant correlation in FL and FW with FG and NFMF, respectively (r=+1.00; P≤0.05) were observed. Likewise, FW with FL (r=+1.00; P≤0.001). High magnitude and significant correlation was found between IL and LPL (r=+1.00; P≤0.01). Similarly, High magnitude and significant correlation links were noticed in NFFF (r=+1.00; P≤0.01), DFFA (r=+1.00; P≤0.05) and NMFP (r=+1.00; P≤0.01) with LW; DFFA with NFFF(r=+1.00; P≤0.05); NMFP with NFFF (r=+1.00; P≤0.05); NFP with NFFP with NFFF(r=+1.00; P≤0.01); SYH with SYP with NFFF(r=+1.00; P≤0.001); FYP with SYP (r=+0.99; P≤0.01), SYH (r=+0.99; P≤0.01) and PL (r=+1.00; P≤0.01); FYH with SYP (r=+0.99; P≤0.01), SYH (r=+0.99; P≤0.01), PL (r=+1.00; P≤0.01) and FYP (r=+1.00; P≤0.001); RT with NSF (r=+1.00; P≤0.05); AAS with NSF (r=+1.00; P≤0.05) and RT (r=+1.00; P≤0.001); SYF with NSF (r=+1.00; P≤0.05). The most important component (PC I) accounted for 2.82E+01 of the eigen value of various traits of viz., TF, P, Mg, Mn, LL, LW, LPL, IL, NFMF, NFFF, DFFA, NFFP, FL, FG, PdL and FW contributed significantly towards variation and remaining contributed nega-tively in PC I. High PCV and GCV were recorded for the TF (24.5398 and 25.1457), LPL (32.812 and 33.0797), IL (26.4953 and 26.6832), NFFF (44.5599 and 45.3748), DFFA (23.9766 and 24.1199), NFFP (60.336 and 61.3191), NMFP (26.8572 and 27.2372), FL (30.2802 and 31.4789), FG (50.0635 and 50.2592), FW (66.1507 and 66.3744), NFP (66.752 and 68.1876), FYP (37.6462 and 38.6746), FYH (37.6464 and 38.6749), SYP (74.9487 and 76.552) and SYH (74.9489 and 76.5522). Moderate PCV and GCV were recorded for antioxidants viz. TP (16.1697 and 16.3706), CUPRAC (17.4532 and 18.1472), FRAP (18.232 and 18.9743), AAF (10.8654 and 10.9649); mineral content including Ca (10.9894 and 13.2227); and physiological traits viz. PL (11.5225 and 15.8628), LL (10.3656 and 10.8454), LW (11.6807 and 12.3559), PdL (10.8469 and 11.4547), RT (19.414 and 19.6855), FT (10.2848 and 10.748), AAF (10.5699 and 11.5069), and SYF (14.5073 and 14.7749). High genetic advance was observed for TP (22.07%), AAF (21.38%), K (67.44%), DFFA (29.85%), NFFP (23.64%), FL (25.74%), FG (49.31%), FW (99.61%), FT (22.68%), NFP (25.29%), NSF (22.62%), FYP (26.93%), FYH (23.88%) and SYP (45.51%).