Our objective: This ethnobotanical study was conducted in the region of El Bioudh Sidi Cheikhe (El Bayadh, Algeria) to gather information on the phytotherapeutic uses practiced in this region. Using questionnaire sheets, a series of ethnobotanical surveys were carried out during the year 2023. The identification of plants collected in the field was carried out in the laboratory. We selected 46 species belonging to twenty-four (24) botanical families, and the list of different families and species of medicinal plants chosen is presented in Figure 1, along with their frequency of citation. The most commonly used family was Asteraceae (07 species) with a percentage of 15.21%, followed by Fabaceae, Solanaceae (04 species) with a percentage of 8.69%, and then Apiaceae, Lamiaceae, Poaceae (03 species) with a percentage of 6.52%. Caryophyllaceae, Tamaricaceae, Verbenaceae (02 species) followed with a percentage of 4.34%. Other families were represented by a single (01) species, each with a common percentage of 2.17%. The most commonly used plant parts (organs) were the leaves with a rate of 60.37%, followed by the seeds with a rate of 21.74%, and then the roots with a rate of 8.70%. The flowers and fruits had the same rate, which was 4.35%. Moreover, the diseases treated by these medicinal plants are dominated by digestive disorders (43.47%), skin disorders (13%), genitourinary disorders (15.21%), and neurological disorders (2.17%). The surveys carried out made it possible to inventory the medicinal species and to collect the maximum information concerning local traditional therapeutic uses. These results can be considered as a source of information for scientific research in the fields of phytochemistry and pharmacology.