Organic farming in guava has opened a new vista for sustainable crop production under this covid pandemic situation where every human being is moving forward for healthy and chemical free fruit production. For keeping the safety rules for human health an experiment was conducted to study the impact of different organic manures solely or in combinations with biofertilizers on fruit quality and relative economics of high density guava during winter season in the experimental farm at Organic Farming Research Centre (OFRC), Chatha at Sher-e-Kashmir University of Agricultural Sciences & Technology, Jammu (J&K). The experiment was conducted on three years old guava trees with 13 treatments alone or in combinations with vermicompost and poultry manure and biofertilizers (Azotobacter and PSB) during the first week of July. The results of the experiment revealed that highest organic carbon (7.6 g kg-1), water holding capacity (52.10 %), soil microbial biomass(97.98 mg kg-1) and lowest bulk density (0.29 g cm-3) were recorded from the with the application of farmyard manure (25%) + vermicompost (50%) + poultry manure (25%) (T12) whereas, highest leaf N, P & K (1.73, 0.23 & 1.28 %) content were obtained with the treatment comprising of full dose of N through PM + Azotobacter + PSB (T9). The same treatment (T9) also recorded highest leaf chlorophyll content to the corresponding value of 9.96 mg g-1 tissue. The data also revealed that full dose of N through poultry manure + Azotobacter+ PSB (T9) recorded highest fruit TSS, pectin, vitamin C and total sugar. It was found that full dose of N through poultry manure+ Azotobacter+ PSB (T9) was considered as best treatment with the maximum profit of Rs. 6,52,888 and benefit cost ratio of 1: 5.26.