The effect of antioxidants on IgG levels in cattle blood can be significant, as IgG is a crucial component of the immune system responsible for providing passive immunity to the animal. Here's how antioxidants may impact IgG levels in cattle: Enhanced Immune Function: Antioxidants such as vitamin E, vitamin C, selenium, and zinc play a vital role in supporting immune function by protecting immune cells from oxidative damage. When antioxidant levels are optimal, the immune system can function more efficiently, including the production and maintenance of IgG levels. The purpose of the study was to determine how antioxidant injections affected the IgG levels in the plasma of crossbred cattle. There were four groups (T1, T2, T3, and T4), each with six crossbred animals. As the control group, group T1 was given only the minimum amount of food. Multimineral injections were given to the T2 group, multivitamin injections to the T3 group, and a combination of multivitamin and multimineral injections to the T4 group. They received injections on the 7, 15, 21, and 30 days prior to delivery. The T4 group exhibited the greatest rise in plasma IgG levels (p<0.05). The T2 group likewise demonstrated a significant rise (p<0.05). Although it wasn't very noticeable, there was an increase in T3-specific IgG levels.