A field experiment was established at Jawaharlal Nehru Krishi Vishwa Vidyalaya, Jabalpur, Madhya Pradesh to find out a suitable crop establishment method (direct seeded rice, system of rice intensification, transplanted rice) and herbicidal applications (bispyribac-sodium at 20 g ha-1, fenoxaprop-p-ethyl at 93 g ha-1, fenoxaprop-p-ethyl at 56 g ha-1) for optimum growth, weed flora, water use efficiency and higher yield in rice. Experiment was laid out in a split plot design with three replications. Herbicide was sprayed at 25 DAS/DAT. Among weed control treatments, hand weeding exhibit maximum grain yield. Among herbicidal application, bispyribac sodium at 20 g ha-1 observed higher crop growth and yield than fenoxaprop-p-ethyl at 93 g ha-1 and fenoxaprop-p-ethyl at 56 g ha-1 maximum plant growth parameters. Among all herbicidal treatments, that post-emergence application of bispyribac-sodium at 20 g ha-1 gave significantly lower total weed density, weed dry weight and higher weed control efficiency at all the stages. The minimum weed index was noted under bispyribac-sodium at 20 g ha-1 in System of Rice Intensification (SRI) treated plots.