Brinjal (Solanum melongena L.) is an important vegetable crop grown in across the world. The production and quality of brinjal is seriously influenced by the attack of insect pests. Two year (2018-19 and 2019-20 Rabi) roving survey revealed that four species of insect pests viz., shoot and fruit borer (L. orbonalis) (4.77-20.47 per cent infestation), whitefly (B. tabaci) (1.48-2.29/plant), jassid (A. biguttula biguttula) (1.94-2.83/plant) and aphid (A. gossypii) (1.09-2.27/plant) and three species of predators viz., ladybird beetle (C. transversalis) (0.37-1.27/plant), green lacewing (Chrysoperla carnea) (0.09-0.29/plant) and spider (Oxyopes sp.) (0.02-0.53/plant) were spatially distributed in all three districts (Hoshangabad, Jabalpur and Chhindwara) and associated with both vegetative and maturity stages of brinjal crop. Moreover, relation of weather variables and weather and crop age based prediction models for major insect pest and their natural enemies were derived through a data generated in a two year field experiment at Rehti, Sehore (Madhya Pradesh). Pearson correlation coefficient revealed that two week prier maximum temp was exhibited significantly positive relation with per cent fruit and shoot borer damage (-0.862**) and count of Ladybird beetle (0.535*). Whereas, jassid (-0.570**), Green lacewing (-0.665**) and whitefly (-0.743**) was significantly negative related with current week (jassid & green lacewing) and one week (whitefly) prier maximum temp, respectively. Likewise minimum temp was also followed similar trend of relation with insect pest and predators. Morning and evening RH had non-significant relation with most of the factors except positive significant with green lacewing. Crop age influenced significantly positive with count of whitefly and shoot and fruit borer and negatively with ladybird beetle. Regression analysis revealed that current week of maximum and minimum temperature, morning and evening RH and crop age were most fitted and accounted 76.9, 77.3 and 94.2 % variability in population dynamics of whitefly (R2 = 0.769), jassid (R2 = 0.773) and shoot and fruit borer damage (R2 = 0.942), respectively. Whereas the similar set of one week and two week prier weather parameters were most fitted for the prediction of green lacewing (R2 = 0.847) and ladybird beetle (R2 = 0.681), respectively. This study will be helpful in management of insect pests through timely application of eco-friendly management practices in the region.