The study was conducted on six clinical cases of diaphyseal femur fractures in dogs of both sex and age ranging from 6 months to 4 years. A Vet Fix system was developed for the present study. This system was used for management of unstable diaphyeseal fractures of long bones. Vet Fix provided axial stability and the clamp and screw controlled shortening and torsional forces. Cases presenting with the history and radiography suggestive of femur fracture were selected for this study. Based on the fracture plan made from preoperative radiographs the implants were selected. The Vet Fix system was applied on the lateral aspect of the femur. The rod was contoured to the shape of the bone during the time of surgery and the clamps were arranged depending upon the fracture configuration intraoperatively. Four dogs started normal weight bearing at rest but favoured affected limb while walking on the second post operative day. Two dogs started partial weight bearing at rest and did not bear weight on affected limb while walking. Primary healing was observed in four dogs. Two dogs showed uneven periosteal reaction with periosteal and intercortical callus indicating secondary healing in progress. The post operative complications encountered was loosening of distal clamp was noticed in one dog and migration of rod through the skin in one dog. Vet Fix system provided adequate stability in combination with ancillary implants such as intramedullary pin and cerclage wire.