There were total 10 newer insecticides viz., Thiamethoxam 25 % WG, thiamethoxam 75 % SG, Acetamiprid 20% SP, Emmamectin benzoate 5% SG, Chlorantraniliprole 18.5% SC, Thiacloprid 21.7% SC, Propargite 57% EC and Tetraniliprole 18.18% SC including one control with water spray were evaluated for their bio-efficacy against major insect-pests of soybean under field conditions. For whitefly management, Thiamethoxam 25 % WG (1.18 nymph and adult/trifoliate leaf) was found most effective after two insecticidal sprays of different insecticides during 2021 and 2022. For leaf feeding insects of soybean i.e., tobacco caterpiler and semiloopers management, Chlorantraniliprole 18.5% SC (0.14 and 3.04 larva/meter row length, respectively) was found most effective after two insecticidal sprays of different insecticides. For stem fly management, Thiamethoxam 75 % SG (23.78% stem tunneling) was found most effective after two insecticidal sprays of different insecticides. For girdle beetle management, Thiacloprid 21.7% SC (3.98% girdle beetle infestation) was found most effective followed after two insecticidal sprays of different insecticides.