Dazomet can effectively suppress the outbreak of blight by killing a variety of nematodes and pathogens in the soil. There are few studies on the application dosage and the uniformity of dazomet by mechanized spreading. The motion model of dazomet, which can be the theoretical basis for experimental study, was obtained by analyzing the motion characteristic of dazomet in the centrifugal disc spreading process. Taking rotation speed of the spreading disk, opening degree, and forward speed as control factors, and the application dosage and the uniformity (transverse coefficient of variation) of dazomet in the designated spreading area as evaluation index, a bench test based on Box-Behnken Design (BBD) test method was carried out. Quadratic regression equations of application and uniformity amount with control factors were established respectively. In the end, a strategy to determine the combination of working parameters was proposed, and a verification test is carried out to confirm the accuracy and rationality of the strategy. The results indicate that the combination of working parameters based on the strategy meets the technical requirements of the dazomet spreading.