Eggplant (Solanum melongena L.) commonly known as brinjal belongs to the family Solanaceae. Brinjal is particularly grown in sub-tropical and tropical regions of the world. It is the most important vegetable in India and is described as “king of vegetables” due to its wide usage in Indian foods. The brinjal crop succumbs to various biotic and abiotic stresses at various stages of growth. There are several environmental, edaphic and plant factors which results in lower production and productivity in brinjal. It is attacked by many fungi, bacteria and viruses. Among various stresses, diseases are the prominent factor in decreasing the production in brinjal. The major diseases which reduces the yield in brinjal is Phomopsis fruit rot caused by Phomopsis vexans. The pathogen is seed-borne and produce large number of conidia which causes infection in brinjal. The devastating diseases such as phomopsis blight should be controlled effectively for increasing its marketability and consumption. The effective fungicides which shows highest average mycelial growth inhibition are carbendazim, propiconazole and hexaconazole among systemic fungicides. An increasing consciousness about environmental pollution due to fungicides and development of fungicide resistance in pathogen population has challenged the plant pathologist to search for eco-friendly tools for Phomopsis vexans management. Seed treatment and spraying of Trichoderma harzianum and Pseudomonas fluorescens are very effective against Phomopsis vexans. Use of botanicals, bioagents are most commonly practiced now a days to avoid the problems created by the fungicides.